WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:endocytic recycling       ID:GO:0032456
C=11; O=2; E=0.02; R=102.31; rawP=0.0002; adjP=0.0606
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000090565 NA RAB11FIP3 RAB11 family interacting protein 3 (class II) 9727 ENSG00000090565
2  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016


Database:biological process       Name:dendrite morphogenesis       ID:GO:0048813
C=76; O=2; E=0.14; R=14.81; rawP=0.0080; adjP=0.3463
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000078018 NA MAP2 microtubule-associated protein 2 4133 ENSG00000078018
2  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:biological process       Name:central nervous system neuron development       ID:GO:0021954
C=51; O=2; E=0.09; R=22.07; rawP=0.0037; adjP=0.3463
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000078018 NA MAP2 microtubule-associated protein 2 4133 ENSG00000078018
2  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:biological process       Name:palate development       ID:GO:0060021
C=70; O=2; E=0.12; R=16.08; rawP=0.0068; adjP=0.3463
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000116132 NA PRRX1 paired related homeobox 1 5396 ENSG00000116132
2  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:biological process       Name:execution phase of apoptosis       ID:GO:0097194
C=228; O=3; E=0.41; R=7.40; rawP=0.0075; adjP=0.3463
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107731 NA UNC5B unc-5 homolog B (C. elegans) 219699 ENSG00000107731
2  ENSG00000213190 NA MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 10962 ENSG00000213190
3  ENSG00000099954 NA CECR2 cat eye syndrome chromosome region, candidate 2 27443 ENSG00000099954


Database:biological process       Name:regulation of apoptotic signaling pathway       ID:GO:2001233
C=66; O=2; E=0.12; R=17.05; rawP=0.0061; adjP=0.3463
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107731 NA UNC5B unc-5 homolog B (C. elegans) 219699 ENSG00000107731
2  ENSG00000213190 NA MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 10962 ENSG00000213190


Database:biological process       Name:extrinsic apoptotic signaling pathway       ID:GO:0097191
C=43; O=2; E=0.08; R=26.17; rawP=0.0026; adjP=0.3463
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107731 NA UNC5B unc-5 homolog B (C. elegans) 219699 ENSG00000107731
2  ENSG00000213190 NA MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 10962 ENSG00000213190


Database:biological process       Name:cell projection morphogenesis       ID:GO:0048858
C=679; O=4; E=1.21; R=3.31; rawP=0.0305; adjP=0.4076
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107731 NA UNC5B unc-5 homolog B (C. elegans) 219699 ENSG00000107731
2  ENSG00000078018 NA MAP2 microtubule-associated protein 2 4133 ENSG00000078018
3  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
4  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:biological process       Name:nucleoside triphosphate metabolic process       ID:GO:0009141
C=475; O=3; E=0.84; R=3.55; rawP=0.0509; adjP=0.4076
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138835 NA RGS3 regulator of G-protein signaling 3 5998 ENSG00000138835
2  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580
3  ENSG00000101892 NA ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 23439 ENSG00000101892


Database:biological process       Name:regulation of nucleoside metabolic process       ID:GO:0009118
C=238; O=2; E=0.42; R=4.73; rawP=0.0663; adjP=0.4076
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138835 NA RGS3 regulator of G-protein signaling 3 5998 ENSG00000138835
2  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:molecular function       Name:adenyl nucleotide binding       ID:GO:0030554
C=1516; O=8; E=2.78; R=2.88; rawP=0.0047; adjP=0.0740
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170390 NA DCLK2 doublecortin-like kinase 2 166614 ENSG00000170390
2  ENSG00000140367 NA UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 92912 ENSG00000140367
3  ENSG00000204580 NA DDR1 discoidin domain receptor tyrosine kinase 1 780 ENSG00000204580
4  ENSG00000126803 NA HSPA2 heat shock 70kDa protein 2 3306 ENSG00000126803
5  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
6  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016
7  ENSG00000165868 NA HSPA12A heat shock 70kDa protein 12A 259217 ENSG00000165868
8  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:molecular function       Name:Rab GTPase binding       ID:GO:0017137
C=46; O=2; E=0.08; R=23.73; rawP=0.0032; adjP=0.0740
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000090565 NA RAB11FIP3 RAB11 family interacting protein 3 (class II) 9727 ENSG00000090565
2  ENSG00000147041 NA SYTL5 synaptotagmin-like 5 94122 ENSG00000147041


Database:molecular function       Name:ATP binding       ID:GO:0005524
C=1482; O=8; E=2.71; R=2.95; rawP=0.0041; adjP=0.0740
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170390 NA DCLK2 doublecortin-like kinase 2 166614 ENSG00000170390
2  ENSG00000140367 NA UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 92912 ENSG00000140367
3  ENSG00000204580 NA DDR1 discoidin domain receptor tyrosine kinase 1 780 ENSG00000204580
4  ENSG00000126803 NA HSPA2 heat shock 70kDa protein 2 3306 ENSG00000126803
5  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
6  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016
7  ENSG00000165868 NA HSPA12A heat shock 70kDa protein 12A 259217 ENSG00000165868
8  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:molecular function       Name:adenyl ribonucleotide binding       ID:GO:0032559
C=1512; O=8; E=2.77; R=2.89; rawP=0.0046; adjP=0.0740
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170390 NA DCLK2 doublecortin-like kinase 2 166614 ENSG00000170390
2  ENSG00000140367 NA UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 92912 ENSG00000140367
3  ENSG00000204580 NA DDR1 discoidin domain receptor tyrosine kinase 1 780 ENSG00000204580
4  ENSG00000126803 NA HSPA2 heat shock 70kDa protein 2 3306 ENSG00000126803
5  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
6  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016
7  ENSG00000165868 NA HSPA12A heat shock 70kDa protein 12A 259217 ENSG00000165868
8  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:molecular function       Name:nucleoside binding       ID:GO:0001882
C=1852; O=8; E=3.39; R=2.36; rawP=0.0153; adjP=0.0747
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170390 NA DCLK2 doublecortin-like kinase 2 166614 ENSG00000170390
2  ENSG00000140367 NA UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 92912 ENSG00000140367
3  ENSG00000204580 NA DDR1 discoidin domain receptor tyrosine kinase 1 780 ENSG00000204580
4  ENSG00000126803 NA HSPA2 heat shock 70kDa protein 2 3306 ENSG00000126803
5  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
6  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016
7  ENSG00000165868 NA HSPA12A heat shock 70kDa protein 12A 259217 ENSG00000165868
8  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:molecular function       Name:purine ribonucleotide binding       ID:GO:0032555
C=1864; O=8; E=3.41; R=2.34; rawP=0.0159; adjP=0.0747
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170390 NA DCLK2 doublecortin-like kinase 2 166614 ENSG00000170390
2  ENSG00000140367 NA UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 92912 ENSG00000140367
3  ENSG00000204580 NA DDR1 discoidin domain receptor tyrosine kinase 1 780 ENSG00000204580
4  ENSG00000126803 NA HSPA2 heat shock 70kDa protein 2 3306 ENSG00000126803
5  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
6  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016
7  ENSG00000165868 NA HSPA12A heat shock 70kDa protein 12A 259217 ENSG00000165868
8  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:molecular function       Name:purine ribonucleoside triphosphate binding       ID:GO:0035639
C=1829; O=8; E=3.35; R=2.39; rawP=0.0142; adjP=0.0747
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170390 NA DCLK2 doublecortin-like kinase 2 166614 ENSG00000170390
2  ENSG00000140367 NA UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 92912 ENSG00000140367
3  ENSG00000204580 NA DDR1 discoidin domain receptor tyrosine kinase 1 780 ENSG00000204580
4  ENSG00000126803 NA HSPA2 heat shock 70kDa protein 2 3306 ENSG00000126803
5  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
6  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016
7  ENSG00000165868 NA HSPA12A heat shock 70kDa protein 12A 259217 ENSG00000165868
8  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:molecular function       Name:ribonucleoside binding       ID:GO:0032549
C=1842; O=8; E=3.37; R=2.37; rawP=0.0148; adjP=0.0747
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170390 NA DCLK2 doublecortin-like kinase 2 166614 ENSG00000170390
2  ENSG00000140367 NA UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 92912 ENSG00000140367
3  ENSG00000204580 NA DDR1 discoidin domain receptor tyrosine kinase 1 780 ENSG00000204580
4  ENSG00000126803 NA HSPA2 heat shock 70kDa protein 2 3306 ENSG00000126803
5  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
6  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016
7  ENSG00000165868 NA HSPA12A heat shock 70kDa protein 12A 259217 ENSG00000165868
8  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:molecular function       Name:transmembrane receptor protein tyrosine kinase activity       ID:GO:0004714
C=67; O=2; E=0.12; R=16.29; rawP=0.0066; adjP=0.0747
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204580 NA DDR1 discoidin domain receptor tyrosine kinase 1 780 ENSG00000204580
2  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:molecular function       Name:purine ribonucleoside binding       ID:GO:0032550
C=1838; O=8; E=3.37; R=2.38; rawP=0.0146; adjP=0.0747
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170390 NA DCLK2 doublecortin-like kinase 2 166614 ENSG00000170390
2  ENSG00000140367 NA UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 92912 ENSG00000140367
3  ENSG00000204580 NA DDR1 discoidin domain receptor tyrosine kinase 1 780 ENSG00000204580
4  ENSG00000126803 NA HSPA2 heat shock 70kDa protein 2 3306 ENSG00000126803
5  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
6  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016
7  ENSG00000165868 NA HSPA12A heat shock 70kDa protein 12A 259217 ENSG00000165868
8  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:cellular component       Name:recycling endosome membrane       ID:GO:0055038
C=33; O=2; E=0.04; R=46.98; rawP=0.0008; adjP=0.0264
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000090565 NA RAB11FIP3 RAB11 family interacting protein 3 (class II) 9727 ENSG00000090565
2  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016


Database:cellular component       Name:dendritic shaft       ID:GO:0043198
C=33; O=2; E=0.04; R=46.98; rawP=0.0008; adjP=0.0264
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000078018 NA MAP2 microtubule-associated protein 2 4133 ENSG00000078018
2  ENSG00000125675 NA GRIA3 glutamate receptor, ionotropic, AMPA 3 2892 ENSG00000125675


Database:cellular component       Name:recycling endosome       ID:GO:0055037
C=75; O=2; E=0.10; R=20.67; rawP=0.0042; adjP=0.0924
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000090565 NA RAB11FIP3 RAB11 family interacting protein 3 (class II) 9727 ENSG00000090565
2  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016


Database:cellular component       Name:microtubule associated complex       ID:GO:0005875
C=104; O=2; E=0.13; R=14.91; rawP=0.0079; adjP=0.1303
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000166963 NA MAP1A microtubule-associated protein 1A 4130 ENSG00000166963
2  ENSG00000078018 NA MAP2 microtubule-associated protein 2 4133 ENSG00000078018


Database:cellular component       Name:dendrite       ID:GO:0030425
C=355; O=3; E=0.46; R=6.55; rawP=0.0103; adjP=0.1360
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000078018 NA MAP2 microtubule-associated protein 2 4133 ENSG00000078018
2  ENSG00000125675 NA GRIA3 glutamate receptor, ionotropic, AMPA 3 2892 ENSG00000125675
3  ENSG00000182580 NA EPHB3 EPH receptor B3 2049 ENSG00000182580


Database:cellular component       Name:cytoskeleton       ID:GO:0005856
C=1790; O=6; E=2.31; R=2.60; rawP=0.0226; adjP=0.1687
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000090565 NA RAB11FIP3 RAB11 family interacting protein 3 (class II) 9727 ENSG00000090565
2  ENSG00000170390 NA DCLK2 doublecortin-like kinase 2 166614 ENSG00000170390
3  ENSG00000166963 NA MAP1A microtubule-associated protein 1A 4130 ENSG00000166963
4  ENSG00000078018 NA MAP2 microtubule-associated protein 2 4133 ENSG00000078018
5  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
6  ENSG00000125675 NA GRIA3 glutamate receptor, ionotropic, AMPA 3 2892 ENSG00000125675


Database:cellular component       Name:cytoskeletal part       ID:GO:0044430
C=1287; O=5; E=1.66; R=3.01; rawP=0.0217; adjP=0.1687
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000090565 NA RAB11FIP3 RAB11 family interacting protein 3 (class II) 9727 ENSG00000090565
2  ENSG00000166963 NA MAP1A microtubule-associated protein 1A 4130 ENSG00000166963
3  ENSG00000078018 NA MAP2 microtubule-associated protein 2 4133 ENSG00000078018
4  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
5  ENSG00000125675 NA GRIA3 glutamate receptor, ionotropic, AMPA 3 2892 ENSG00000125675


Database:cellular component       Name:microtubule cytoskeleton       ID:GO:0015630
C=863; O=4; E=1.11; R=3.59; rawP=0.0230; adjP=0.1687
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000090565 NA RAB11FIP3 RAB11 family interacting protein 3 (class II) 9727 ENSG00000090565
2  ENSG00000166963 NA MAP1A microtubule-associated protein 1A 4130 ENSG00000166963
3  ENSG00000078018 NA MAP2 microtubule-associated protein 2 4133 ENSG00000078018
4  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469


Database:cellular component       Name:endocytic vesicle       ID:GO:0030139
C=149; O=2; E=0.19; R=10.40; rawP=0.0156; adjP=0.1687
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000013016 NA EHD3 EH-domain containing 3 30845 ENSG00000013016
2  ENSG00000125675 NA GRIA3 glutamate receptor, ionotropic, AMPA 3 2892 ENSG00000125675


Database:cellular component       Name:intracellular non-membrane-bounded organelle       ID:GO:0043232
C=3800; O=9; E=4.90; R=1.84; rawP=0.0388; adjP=0.2328
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000090565 NA RAB11FIP3 RAB11 family interacting protein 3 (class II) 9727 ENSG00000090565
2  ENSG00000170390 NA DCLK2 doublecortin-like kinase 2 166614 ENSG00000170390
3  ENSG00000166963 NA MAP1A microtubule-associated protein 1A 4130 ENSG00000166963
4  ENSG00000078018 NA MAP2 microtubule-associated protein 2 4133 ENSG00000078018
5  ENSG00000116132 NA PRRX1 paired related homeobox 1 5396 ENSG00000116132
6  ENSG00000160469 NA BRSK1 BR serine/threonine kinase 1 84446 ENSG00000160469
7  ENSG00000099954 NA CECR2 cat eye syndrome chromosome region, candidate 2 27443 ENSG00000099954
8  ENSG00000101892 NA ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 23439 ENSG00000101892
9  ENSG00000125675 NA GRIA3 glutamate receptor, ionotropic, AMPA 3 2892 ENSG00000125675




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).